Ipamorelin

Ipamorelin Peptide — Research Overview Ipamorelin is a synthetic pentapeptide classified as a Growth Hormone Secretagogue (GHS). It works by selectively activating ghrelin receptors (GHS‑R1a) in the pituitary gland, which stimulates natural growth hormone (GH) release. Research shows that Ipamorelin increases GH without significantly affecting other hormones such as prolactin or ACTH. Key Research Findings

• Supports Natural GH Release Studies show Ipamorelin can significantly increase growth hormone levels, which may influence IGF‑1 activity, tissue repair, and cellular growth.
• Muscle & Bone Research Experimental models indicate potential anabolic effects, including improved muscle growth signals and increased bone mineral content.
• Gastrointestinal Function Research suggests Ipamorelin may help improve gastric emptying and support healthy digestive motility through ghrelin‑related pathways.
• Appetite & Weight Regulation In laboratory studies, Ipamorelin has been shown to increase appetite and body weight, likely due to its ghrelin‑mimicking activity and effects on energy balance.
• Nitrogen Balance & Recovery Research indicates Ipamorelin may help improve nitrogen retention during catabolic states, supporting overall anabolic recovery.

Molecular make-up

• Molecular Formula: C₃₈H₄₉N₉O₅
• Molecular Weight: 711.86 g/mol
• Alternate Names: NNC 26-0161